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Twitches or jerks - something like a startle reflex. In combivent respimat como se usa beatifically one embodiment, the method comprises introducing into an organism a target gene of interest which is under the control of at least one tet operator and an expressible nucleotide sequence encoding a revTetR, and contacting the organism with a concentration of tetracycline or tetracycline analog sufficient to alter the level of transcription of the target gene.
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